Review of Active Compounds from Medicinal Plants with Antihyperglycemic Efficiency on Translocation and Expression of Glucose Transporter 4 on Muscle and Adipose Tissue

Glucose transporter’s mechanism is influenced by the presence of insulin, especially GLUT4 which acts on muscle, adipose, and brain tissue. Medicinal plants with active compounds that were able to regulate expression translocation GLUT helps in treatment insulin resistance hyperglycemia. This study aimed determine isolated from medicinal have antihyperglycemic activity muscle adipose The research method used was searching literature electronically keywords "Plant Isolation", "Chemical Compounds", "Antihyperglycemic Activity", "Glucose transporter (GLUT) 4". Literature sources form international national journals been found several sites, such as NCBI, Elsevier Pubmed, others. A search selected 2016 2021. data analyzed using PRISMA (Prefered Reporting Items for Systematic Review Meta-analyses) method. results showed substances contained plant increasing skeletal cells, adipocytes, tested-animal models DM.